Flotillin function
Web8.2 Flotillins. Flotillin-1 and -2 (also called reggie-2 and -1, respectively) are ubiquitously expressed, evolutionary conserved peripherally membrane-associated proteins of approximately 48 kDa. Palmitoylation on cysteine 34 is essential for membrane association of flotillin-1 ( Morrow et al., 2002) and myristoylation of glycine 2 for that of ... WebNov 27, 2009 · These results imply that flotillins are conserved between plants and animals. The conserved subcellular localization suggests the possibility of conserved function(s). In this work, we employ a reverse genetics approach to investigate the role of the Medicago truncatula flotillin-like gene family (FLOTs) in symbiosis.
Flotillin function
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WebJun 1, 2015 · Here, we explored flotillin-1-mediated regulation of insulin-like growth factor-1 (IGF-1) signaling. Flotillin-1-deficient cells exhibited a reduction in the activation of IGF-1 receptor (IGF-1R), ERK1/2 and Akt pathways, and the transcriptional activation of Elk-1 and the proliferation in response to IGF-1 were reduced in these cells. WebMay 26, 2014 · The ubiquitous and highly conserved flotillin proteins, flotillin-1 and flotillin-2, have been shown to be involved in various cellular processes such as cell adhesion, signal transduction through receptor tyrosine kinases as well as in cellular trafficking pathways. Due to the fact that flotillins are acylated and form hetero-oligomers, …
WebFlotillin-1 and -2 ... At a Keystone Symposium on Lipid Rafts and Cell Function in 2006, a consensus was reached that the term ‘lipid rafts’ should be changed to ‘membrane rafts’ … WebJan 21, 2014 · The function of flotillin microdomains is not fully understood, but they are likely to be important for linking the plasma membrane and the cytoskeleton [10] – [12], for signaling events [13], …
WebNov 27, 2009 · These results imply that flotillins are conserved between plants and animals. The conserved subcellular localization suggests the possibility of conserved function(s). … WebAug 1, 2024 · Flotillin-1 and -2 are markers of membrane rafts but their true endothelial function is unknown. We hypothesized that flotillins are required for TLR signaling in …
WebFeb 19, 2014 · For a review on flotillin functions in general, the reader is referred to two recent review articles [1,2]. The MAP kinase signaling cascade is the canonical …
WebJan 21, 2014 · The function of flotillin microdomains is not fully understood, but they are likely to be important for linking the plasma membrane and the cytoskeleton –, for signaling events , , for regulating … theory test uk 2023Webflotillin-1 and flotillin-2 were found, e.g. in murine lung, thymus, bladder, cerebrum and hypothalamus tissue lysates (24, our unpublished results). Additionally, it has been … shs school mapWebFlotillin-1 is a close homolog of the Epidermal Surface Antigen (ESA/Flotillin-2), which also colocalizes in the caveolae. Thus, Flotillin-1 and its relative ESA/Flotillin-2 are now … shs schools in ashanti regionWebThe function of flotillin 1 has not been determined. Synonyms. DADB-118P11.2; Flot1; flotillin 1; Flotillin-1; I79_013152; integral membrane component of caveolae; … shs school security system designertheory test uk downloadWebJan 1, 2015 · To investigate the potential functions of FLOT2 in cervical cancer progression, we measured the expression pattern of FLOT2 in 115 archived cervical … theory test uk 2020 freeWebJun 1, 2015 · Flotillin-1 (also known as reggie-2) and flotillin-2 (also known as reggie-1) are membrane-associated oligomeric proteins that are ubiquitously expressed ( Lang et al., 1998; Neumann-Giesen et al., 2004; Solis et al., 2007; Stuermer et al., 2001 ). shs school website