Cyclophosphamid synthese
WebCyclophosphamide C7H15Cl2N2O2P CID 2907 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … WebCyclophosphamide is a cytotoxic (cytostatic), cell cycle nonspecific, antiproliferative agent which is used in such diverse medical problems as neoplasia, tissue transplantation and …
Cyclophosphamid synthese
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WebJul 18, 2024 · Cyclophosphamide (CPA) represents a widely used anti-cancer prodrug that is converted by liver cytochrome P450 (CYP) enzymes into the primary … WebBackground. People with connective tissue disease such as rheumatoid arthritis and systemic sclerosis may develop a group of lung diseases called interstitial lung disease. This can affect breathing and quality of life, and can lead to a reduced life span. A drug called cyclophosphamide has been useful in treating other illnesses, but it has ...
WebCyclophosphamide. Synthesis and properties of this drug are described in Chapter 30. Besides being used as an alkylating agent in cancer chemotherapy, cyclophosphamide is a unique drug when used as an immunosuppressant. First, it is … WebSep 1, 2024 · Cyclophosphamide is an alkylating chemotherapy drug that stops the cell division by cross-linking DNA strands and decreasing DNA synthesis. 1 Cyclophosphamide has many side effects like most of the other chemotherapy drugs such as bone marrow suppression, hepatotoxicity, immunosuppression, cardiotoxicity, …
WebPhosphorsäure-[di-(2-chloraethyl)]-amid-dichlorid (3) reagiert unter den Bedingungen der Cyclophosphamid-Synthese mit Oxo-(4-methoxyphenyl)-[4-(3-hydroxypropyl)-aminophenyl]-methan (10) nicht unter Bildung des Cyclophosphamidderivats 11, sondern von Oxo-(4-methoxy-phenyl)-[4-(3-chlorpropyl)-aminophenyl]-methan (12).Auch tritt in … WebMar 10, 2015 · Alkylating agents are a class of antineoplastic or anticancer drugs which act by inhibiting the transcription of DNA into RNA and thereby stopping the protein synthesis. Alkylating agents substitute alkyl groups for hydrogen atoms on DNA, resulting in the formation of cross links within the DNA chai …
Cyclophosphamid wird bei einer Reihe von bösartigen Erkrankungen (Krebserkrankungen) als Zytostatikum eingesetzt. Zumeist erfolgt der Einsatz in Kombination mit anderen Zytostatika. • Mammakarzinom (CMF-Schema: Cyclophosphamid, Methotrexat, 5-Fluoruracil) • Weichteilsarkome • Hodgkin-Lymphom
http://www.bccancer.bc.ca/drug-database-site/drug%20index/cyclophosphamide_monograph_1june2013_formatted.pdf generac 7122 speedwash 3200 psi orangeWebSynthesis and antitumor properties of activated cyclophosphamide analogues. A series of 5- and 6-substituted cyclophosphamide analogues has been prepared, and their 31P … generac 7102 oil heaterWebSynthesis and antitumor activity of cyclophosphamide analogs. 2. Preparation, hydrolytic studies, and anticancer screening of 5-bromocyclophosphamide, 3,5 … dead or alive 6 hayateWebNational Center for Biotechnology Information generac 7132 electric start pressure washerWebOrganophosphorus chemistry is the scientific study of the synthesis and properties of organophosphorus compounds, which are organic compounds containing phosphorus. [1] They are used primarily in pest control as an alternative to chlorinated hydrocarbons that persist in the environment. Some organophosphorus compounds are highly effective ... generac 7170 mobile link wifi ethernetWebThis procedure was utilized in the synthesis of enantiomers of ifosfamide, cyclophosphamide, and trofosfamide [248,249]. The development of its structure has been enrolled for the synthesis of CBM-11 (Scheme 8.46). So, replacing the carcinogenic aziridine, [248] 2-chloroethylamine hydrochloride was utilized for the synthesis of … generac 7170 mobile link wifiWebFeb 17, 2024 · Mechanism of Action. Cyclophosphamide is an alkylating agent that prevents cell division by cross-linking DNA strands and decreasing DNA synthesis. It is … generac 7117 air conditioner